Your endocannabinoid system is key for establishing and maintaining health.

Thus far, cannabis is the only plant to produce cannabinoids. This includes the famous psychoactive, tetrahydrocannabinol (THC) and the popular cannabidiol (CBD). Yet, cannabis isn’t the only supplement that engages with your endocannabinoid system (ECS).

The ECS is a major communication network in the body. In many ways, the ECS provides the signaling mechanisms that allow the body and the brain to coordinate with each other. Thanks to the help of the ECS, the body and the brain can synchronize in response to their environment.

This system includes tiny signaling molecules called endocannabinoids, as well as the cell receptors with which they connect.

Cannabinoid receptors are found on just about every organ in the body. They are also present on immune cells, guiding the body’s response to illness. This means that an imbalance in the ECS can have far-reaching health ramifications.

Although cannabis can supplement or bolster ECS function when necessary, endocannabinoids are like the body’s own cannabis. 

Anandamide is one of two primary endocannabinoids. The second is 2-Arachidonoylglycerol (2-AG). The body produces these chemicals naturally from dietary sources. Both diet and lifestyle are major influences to overall endocannabinoid health.

To ensure that your ECS is healthy and thriving, here are five ways to support the endocannabinoid system with lifestyle:

1.) Exercise

Man drinking water
Be sure to also drink plenty of water!

Have you ever wondered what causes the “runner’s high”? While for years feel-good endorphins were thought to be the culprit, evidence shows that exercise boosts the production of an endocannabinoid called anandamide.

Anandamide, often referred to as “the bliss molecule”, is released after exercise and contributes to a mellow, perhaps slightly euphoric feeling post-exercise.

Exercise and physical movement are the first and foremost ways to enhance the ECS.

Those with sedentary lifestyles, such as office workers, students, and those with limited mobility, miss out on the opportunity to cultivate the production of endocannabinoids in the body.

The U.S. Office of Disease Prevention and Health Promotion recommends at least two and a half hours of moderate physical activity is recommended per week.

For those who struggle with chronic pain or have difficulty getting adequate exercise, cannabis may provide temporary relief. However, moving your body and staying active are essential for sustainable endocannabinoid health.

2.) A diet rich in healthy fats

Movement releases endocannabinoids, but diet is critical for manufacturing these important molecules. Endocannabinoids are products of fat, which means that eating healthy fats is vital for the health of the system as a whole.

Polyunsaturated fats have been shown to be particularly beneficial for the ECS. Specifically, omega-3 and omega-6 essential fatty acids.

In fact, research shows that intake of omega-3 fatty acids can increase the expression of cannabinoid receptors. Notably, the CB1 receptor. Greater receptor expression enhances the abilities of anandamide, which provides feelings of bliss and pain relief.

The two primary endocannabinoids are derived from dietary omega-6 fatty acids. These fatty acids are found in poultry, eggs, whole grains, hemp, and seed oils.

Those following a traditional Western diet typically have high intakes of omega-6 fatty acids. However, both omega-6 and omega-3 fatty acids need to be consumed in a fairly even ratio to benefit the ECS.

To make sure the ratio between the two types of fat is as equal as possible, it is recommended to eat a diet rich in foods that contain healthy fats. Particularly those of the omega-3 variety.

Food sources of omega-3 fatty acids include fish, shellfish, algae, flax, hemp, walnuts, and pasture-raised eggs. The omega-3s found in fish and algae are easier for the human body to metabolize than the forms found in nuts and seeds.

3.) Herbs and probiotics

Apart from dietary fat, incorporating a wealth of herbs and spices into your foods provides excellent lifestyle support for the endocannabinoid system. Herbs and spices are among the most nutritionally dense foods around.

A well-rounded diet in general is very important for your health.

While it is certainly possible to use fresh cannabis as a way to add flavor and amp up the therapeutic potential of a meal, research shows that there are several different plants that engage the ECS.

Some of these plants include:


Turmeric (curcumin)

Black pepper



Kava kava

Maca Root




There is also some early evidence that some strains of bacteria can modulate the ECS. One such strain is Lactobacillus acidophilus, which may lend a hand in pain relief via the cannabinoid system. This bacteria is commonly found in probiotic supplements.

Eating prebiotic foods, which are foods that bacteria like to eat, is thought to encourage a healthy microbial community in the gut. Some of these foods include leeks, onions, garlic, and Jerusalem artichoke. 

4.) Stress management

Woman practicing yoga
Stress management is also crucial for a healthy lifestyle.

Exercise and food are the two primary ways to enhance your endocannabinoid system. However, in order to digest your food properly, it’s important to reduce negative stress.

When the body is in a “fight or flight” mode, digestion and immune function slow down. This means that not only are you less likely to fully process nutrients from food, but you’re more prone to infection which can throw the whole body off kilter.

Whether you’re under the gun at work or are simply trying to manage the stress of having a chronic health condition, incorporating stress management techniques is vital for the health of the body in its entirety.

Some simple and common stress-reduction techniques include:




●Light exercise

●Slow, deep breathing

●Spending time in nature

5.) Sleep

Woman waking up from sleep
Are you getting enough sleep every night?

The ECS is one more reason to get a good night’s rest. The ECS influences circadian rhythm, which is the body’s internal clock. Research suggests that when you are sleep deprived, levels of the endocannabinoid 2-AG increase.

In a 2016 study, 14 human participants got an average of four and a half hours of sleep per night over a four day period.

During this time, the participants’ levels of 2-AG increased. And so did their appetites. The participants ate an average of 20 percent more with sleep deprivation, which is about 400 extra calories.

Normally, 2-AG peaks during mid-day and gradually lowers at it gets closer to bedtime. In the afternoon, this chemical helps signal that it’s time to wind down for dinner. However, without adequate sleep, levels of this endocannabinoid spiked higher than normal and stayed elevated for longer.

In this study, researchers speculated that chronic sleep deprivation contributes to obesity via the endocannabinoid system.

To avoid this problem, get some rest! The U.S. Centers for Disease Control recommends that adults get a minimum of seven hours of sleep per night. Those under the age of 18 and over the age of 60 need more, at least eight to 10 full hours.